The same combination of these two mutations, known as L452R and E484Q, the latter of which is closely related to a more well-known mutation known as E484K.
The L452R mutation became well known in California as one found in the California variant (B.1.427/B.1.429), resulting in a strain that is believed to make the virus more infectious and might cause reduced immunity in people who have been vaccinated.
The E484Q mutation is closely related to the E484K mutation, which has been found in variants first identified in South Africa (B.1.351); Brazil (P.1 and P.2) and New York (B.1.526). The E484K mutation is also concerning because it might give the virus the ability to partly evade the immune system's protective response among inoculated people or those who have survived a conventional COVID-19 illness.
"What we don't know is how those [two mutations] will behave when they're put in the same virus," Pinsky said. "There's a reasonable amount of information about those [two mutations] individually. But will it be worse if they're together? We don't really know how they're going to interact."
The Stanford lab routinely performs genetic analysis for coronavirus specimens among COVID-19 patients in the Bay Area. They screen for three worrisome mutations: L452R, E484K, and N501Y. The N501Y mutation — thought to increase the transmissibility of the coronavirus — is found in the U.K. variant (B.1.1.7), as well as the South African variant and one of the Brazilian variants (P.1).
HaHaHello
2021-4-7 21:49:23
Japan's Osaka cancels Olympic torch run
Japan's western region of Osaka on Wednesday cancelled Olympic torch events scheduled across the prefecture, as record infections prompted its government to declare a medical emergency.
Health authorities fear a virus variant is unleashing a fourth wave of infections just 107 days before the Tokyo Olympics begin, with a vaccination drive still at an early stage.
HaHaHello
2021-4-8 07:03:19
All the government want to kill their citizens.
Just think about Hong Kong, we (Hongkongers) have done a good job to fight the Chinese virus, so 777 wants us to take the vaccine. Since the vaccinating started, 15 deaths after taking the vaccine, while only 4 Covid-19 deaths in Hong Kong.
HaHaHello
2021-4-8 07:04:20
54,740 new cases and 276 new deaths in Turkey
Both are new natioanl records!
HaHaHello
2021-4-8 07:28:44
126,315 new cases (new national record after new national record and after new natioanl record) and 684 new deaths in India
HaHaHello
2021-4-9 07:28:07
23,683 new cases (new national record) and 290 new deaths in Argentina
HaHaHello
2021-4-9 08:03:31
131,893 new cases (new national record) and 802 new deaths in India
Keep worsening.
HaHaHello
2021-4-9 09:03:41
Brazil
Sao Paulo, the country's biggest city, on Wednesday said it would begin opening some 600 new graves per day, well beyond the record of 426 burials in a day on March 30. The city is also preparing plans for a "vertical cemetery," a crypt with 26,000 drawer-like graves that can be build in 90 days once approved.
HaHaHello
2021-4-9 09:07:31
Countries worldwide hit new records for virus cases, deaths
And do forget this: Winter is coming to Brazil. God knows how many wil die in the winter.