HaHaHello
2020-11-27 10:20:47
108,063 new cases and 1,306 new deaths in the United States
Because of the Thanksgiving holiday, most of the states have not reported mew cases ad new deaths.
Ads
HaHaHello
2020-11-27 12:16:34
Questions emerge about results of AstraZeneca vaccine
A manufacturing error is raising questions about the early results of the coronavirus vaccine candidate produced by AstraZeneca and Oxford University, which jointly acknowledged the mistake Wednesday.
In announcing results of the vaccine trials Monday, AstraZeneca said it had yielded up to 90% effectiveness and an average of 70% based on groups that got different doses. Surprisingly, the group that received half a dose first, followed by a full dose, registered a higher efficacy than those who got two full doses.
Oxford said in a statement that some of the vials used in the trial didn’t have the right concentration of vaccine, so some volunteers got a half dose. The university said it discussed the problem with regulators and agreed to complete the late-stage trial with two groups. The manufacturing problem has been corrected, according to the statement.
The group that received the two full doses, which generated 62% effectiveness, was more than three times larger than the other one — 8,895 people compared to 2,741. That led to concerns about the statistical reliability of the 90% efficacy the smaller cluster attained. In addition, none of the volunteers in the low-dose group were over 55, an issue because younger people tend to mount a stronger immune response than older ones, which could skew the results.
Keeping worsening.